MEXIDOL ® (Emoxypine)

Mexidol® (Emoxypine) is an antioxidant that is produced in Russia. Its chemical structure resembles that of vitamin B6. Mexidol is a membrane protector that increases the body’s resistance to various damaging factors such as shock, hypoxia, ischemia, and cerebral circulation disorders. This medication is known to improve cerebral circulation and microcirculation and increase dopamine in the brain.

Synonyms	Emoxypine / 2-ethyl-6-methyl-3-hydroxypyridine / Mexifin
Form:	30 pills of 125mg / 10 vials of 2 ml
Active ingredient:	Ethylmethylhydroxypyridine succinate (2-ethyl-6-methyl-3-hydroxypyridine) – 125 mg in pills or 50 mg/1 ml in vials
Excipients for pills:	Lactose monohydrate – 97.5 mg, povidone – 25 mg, magnesium stearate – 2.5 mg. Film coat: opadrai II white 33G28435 – 7.5 mg (hypromellose 3 mg, titanium dioxide – 1.875 mg, lactose monohydrate – 1.575 mg, polyethylene glycol (macrogol) – 0.6 mg, triacetin – 0.45 mg).
Excipients for vials:	Sodium metabisulfite – 0.4 mg, water for injection – up to 1 ml.
СAS Number:	2364-75-2
ATC code:	N07XX
Pharmacological action:	Antioxidant, anxiolytic, anti-hypoxic, anticonvulsant, anti-ischemic, nootropic, neuroprotective, anti-inflammatory, and cardioprotective
Shelf life:	3 years. Do not use it beyond the expiration date printed on the package.
Storage conditions:	Store in a dry dark place at temperatures no higher than 25°C (77°F). Keep out of reach of children.
Terms of release:	Over-the-counter
Manufacturer:	Pharmasoft, Russia. https://pharmasoft.ru/

 

What is Mexidol?

Mexidol is an inhibitor of free-radical processes and membrane protector with anti-hypoxic, stress-protective, nootropic, anticonvulsant, and anxiolytic action.

It is a unique development of the Russian pharmaceutical industry. The development of Emoxypine (Mexidol) is closely associated with the name of the Soviet chemist NN Semenov, who was awarded the Nobel Prize in Chemistry. The drug has been in clinical practice since the 1990s. Click on Research tab above and find a lot of Mexidol research papers.

 

 

What is Mexidol Pharmacology?

Mexidol has antioxidant, anti-hypoxic, and membrane-protective properties. The presence of succinate in the structure of Mexidol is of fundamental importance for the manifestation of its pharmacological effects, since succinate is functionally significant for many processes in the body. In particular, it is a substrate for increasing the energy metabolism in the cell. Due to its properties, free radicals, which have a damaging effect on cellular structures, are deactivated.

Mexidol reduces the viscosity of the membrane and increases its fluidity. The drug preserves the structural and functional organization of membranes and improves synaptic transmission. It enhances the compensatory activation of aerobic glycolysis and activates the energy-synthesizing functions of mitochondria.

In conditions of coronary insufficiency, the drug increases the collateral blood supply of the ischemic myocardium, preserves the integrity of cardiomyocytes, and maintains their functional activity.

What are the Benefits of Mexidol?

• Mexidol improves the blood supply of the brain, improves rheological properties of blood, and reduces platelet aggregation.
• The drug lowers the level of total cholesterol and low-density lipoproteins.
• Mexidol exhibits anti-stress action, normalizes somatic-vegetative disorders and restores sleep-wake cycles.
• It can restore disrupted learning and memory processes, and reduces dystrophic and morphological changes in various structures of the brain, improving congitive functions.
• Mexidol has a pronounced antitoxic effect in patients with a withdrawal syndrome. It eliminates neurological and neurotoxic manifestations of acute alcohol intoxication.
• Mexidol improves the functional state of the ischemic myocardium.

An important advantage of Mexidol is that it stacks well with most nootropics, for example Meldonium. Besides, Mexidol enhances the effect of tranquilizers, neuroleptics, antidepressants, hypnotics, and anticonvulsants. Thus with Mexidol it is possible to reduce their doses and diminish some side effects.

What is the Intended Uses of Mexidol?

Mexidol is effective in the treatment of acute and chronic diseases caused by ischemia and hypoxia. Mexidol is known to treat the followings diseases:

• Neurology: vegetovascular dystonia, acute cerebral circulation disorders, cognitive problems associated with cerebral arteriosclerosis (impaired memory, speech, loss of basic skills, etc.), traumatic brain injury;
• Cardiology:  for the complex treatment of ischemic heart disease;
• Psychiatry: withdrawal syndrome (alcohol or drug withdrawal), anxiety disorders, neurosis, intoxication with drugs from the group of antipsychotics;
• Surgery: for the complex treatment of acute purulent-inflammatory processes in the peritoneum.

Where Can I Order Mexidol Online?

You can buy Mexidol (Emoxypine) online from different vendors. CosmicNootropic offers Mexidol in packs of 30x125mg pills or 10x2ml vials. We offer worldwide shipping with volume discounts! Always be sure to do your research before purchasing any nootropic supplement to ensure you are getting a quality product.

You can order Mexidol and get it delivered to the USA, Europe, the UK, Asia, and many other regions and countries via CosmicNootropic.

In our store you can also find several analogues of Mexidol, namely Ethoxidol and BrainMax. Be sure to check them out and choose which one works best for you!

 

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Legal Disclaimer
This product has not been approved by the US FDA. All statements on this page are for informational purposes only and have not been evaluated by the US FDA.
This product is not intended to diagnose, treat, cure, or prevent any disease. See more

What is Mexidol Dosage?

The drug is taken orally, 1-2 pills 3 times a day. The maximum daily dose is 800 mg (6 pills). The common duration of therapy is 2–6 weeks.

The course duration of the alcohol abstinence treatment is 5–7 days.

The duration of treatment in the case of ischemic heart disease is 6–8 weeks or more.

Mexidol Contraindications

Hypersensitivity, acute kidney and liver diseases, pregnancy, and lactation.

Mexidol Side Effects

Side effects of Mexidol are rare. They include nausea, dry mouth, and allergic reactions.

Mexidol Overdose

The patient may feel drowsiness in case of an overdose. Hence special caution must be taken when driving vehicles and engaging in other potentially dangerous activities.

 

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