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MEBICAR
18 Reviews
Description
Dosage
Research
Reviews
Mebicar is an anxiolytic medication with a chemical structure similar to metabolites in the human body. It does not have a negative effect on mental or physical performance and can be used as a daytime tranquilizer. Mebicar can treat depression, reduce anxiety, improve sleep, enhance cognitive functions, and assist in smoking cessation.
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| Synonyms | Mebicar / Temgicoluril / Tetramethylglycoluril / Mebicarum / Mebikar / 1,3,4,6-Tetramethylglycoluril |
| Form: | 20 pills of 300mg / 20 pills of 500mg |
| Form description: | Round, flat cylindrical tablets of white or almost white color with a facet and a break line. |
| Active ingredient: | Tetramethyltetraazabicyclooctandionum |
| Excipients: | Methylcellulose, calcium stearate. |
| СAS Number: | 10095-06-4 |
| ATC code: | N06BX21 |
| Pharmacological action: | Anxiolytic |
| Shelf life: | 4 years. Do not use it beyond the expiration date printed on the package. |
| Storage conditions: | Store in a dry dark place at temperatures no higher than 25°C (77°F). Keep out of reach of children. |
| Terms of release: | Requires prescription |
| Manufacturer: | TatChemPharmPreparaty, Russia / Latvia |
What is Mebicar?
Mebicar is a daytime tranquilizer. Mebicar belongs to a group of non-benzodizepam tranquilizers. From the chemical perspective, it is a derivative of carbamide, an endogenous metabolite, which explains why the compound is 150 times less toxic than Diazepam.
What is the Mechanism of Action of Mebicar?
Mebicar affects the emotiogenic zones of the hypothalamus. It has an effect on 4 major neurotransmitter systems: GABAergic, cholinergic, serotonergic, and adrenergic. It contributes to their balance and integration without a peripheral adrenoceptor-blocking effect.
It decreases brain norepinephrine levels and increases brain serotonin levels without modulating dopaminergic systems or cholinergic systems.
Here you can find the script of the video.
What are the Benefits and Effects of Mebicar?
- Mebicar can prevent and reduce anxiety, fear, tension, and irritability. Its anxiolytic effect is not accompanied by muscle relaxation, impaired coordination of movements, an elevated mood, a feeling of euphoria, or reduced mental or physical activity, so Mebicar can be used during the daytime.
- Mebicar can enhance the effect of hypnotics and improve disturbed sleep.
- Mebicar is said to relieve nicotine withdrawal.
- Mebicar has a nootropic effect. It improves cognitive functions, attention, and mental performance without stimulating delirium or pathological emotional activity.
What is Mebicar Used For?
You can use Mebicar to treat the following symptoms:
- Asthenic disorders;
- Depressions with anxiety;
- Various conditions characterized by reduced mental productivity;
- Extreme work conditions, e.g. excessive mental or physical exertion;
- Nicotine withdrawal;
- Impaired memory formation.
Where Can I Order Mebicar Online?
You can buy Mebicar online from different vendors. CosmicNootropic offers Mebicar in packs of 20x300mg pills and 20x500mg pills. We offer worldwide shipping with volume discounts! Always be sure to do your research before purchasing any nootropic supplement to ensure you are getting a quality product.
You can order Mebicar and get it delivered to the USA, Europe, the UK, Asia, and many other regions and countries via CosmicNootropic.
Legal Disclaimer
This product has not been approved by the US FDA. All statements on this page are for informational purposes only and have not been evaluated by the US FDA.
This product is not intended to diagnose, treat, cure, or prevent any disease. See more
What is Mebicar Dosage?
The recommended dose is 900–1800 mg per day: 300–600 mg 3 times a day. The duration of treatment can vary from several days to 2 months.
If taken to relieve nicotine withdrawal symptoms, the recommended dose is 300–900 mg three times a day for 5-6 weeks.
What are the Side Effects of Mebicar?
Possible side effects include allergic reactions (itchy skin), headaches, hypotension (low blood pressure), and low body temperature.
Overdose
An increase in potential side effects.
Note
Anecdotal reports in Russia show that Mebicar provides a good rapid effect in the majority of cases without causing sleepiness and grogginess. However, in 8–12% of all cases, the drug appears either to be ineffective or to cause side effects.
OFFICIAL INSTRUCTION
- Zimakova et al (1980) Effect of mebikar on the state of animals under extreme conditions https://www.ncbi.nlm.nih.gov/pubmed/7439369
- Valdman et al (1980) Characteristics of the psychotropic spectrum of action of mebicar https://www.ncbi.nlm.nih.gov/pubmed/6104993
- S Kirshin, I Zimakova (1982) GABA-ergic component in the action of the tranquilizing agent mebikar https://www.ncbi.nlm.nih.gov/pubmed/7075749
- Zimakova et al (1986) Evaluation of the nootropic effect of mebikar in clinical practice https://www.ncbi.nlm.nih.gov/pubmed/3770177
- Zalesov et al (1988) Experimental and clinical study of the effectiveness of the combined use of anticonvulsants and tranquilizers in epilepsy https://www.ncbi.nlm.nih.gov/pubmed/3188750
- Chutko et al (2009) Adaptol in the treatment of ADHD https://www.ncbi.nlm.nih.gov/pubmed/19738569
- Mokina et al (2009) Experience of application of adaptol in treatment of chronic fatigue syndrome in patients with chronic cerebral ischemia https://www.ncbi.nlm.nih.gov/pubmed/19685596
- Chutko et al (2009) The use of adaptol in the treatment of tick hyperkinesis is children https://www.ncbi.nlm.nih.gov/pubmed/20209680
- Chutko et al (2010) Clinical and neurophysiological study of the efficacy of adaptol in the treatment of emotional burn-out https://www.ncbi.nlm.nih.gov/pubmed/21183911
- K Tursunova, L Chutko (2011) Adaptol in the treatment of chronic cervicogenic headache https://www.ncbi.nlm.nih.gov/pubmed/21905338
- E Barantsevich, O Posokhina (2011) Clinical-neurophysiological study of efficacy of adaptol in discirculatory encephalopathy https://www.ncbi.nlm.nih.gov/pubmed/22027612
- V Mkrtchian, L Kozhokova (2012) Adaptol-verges of possible https://www.ncbi.nlm.nih.gov/pubmed/23534281
- Shilina et al (2013) Efficacy of adaptol and the possibility of its differential use in patients with anxiety disorders after myocardial infarction https://www.ncbi.nlm.nih.gov/pubmed/24261227
- S Duma et al (2013) Efficiency of using the anxiolytic adaptol in the combination therapy of arterial hypertension in women https://www.ncbi.nlm.nih.gov/pubmed/23808300
- Orlov et al (2014) Clinical efficiency of combined therapy using adaptol for atopic dermatitis https://www.ncbi.nlm.nih.gov/pubmed/25026806
- Chutko et al (2014) Asthenic disorders in children and their differentiated treatment https://www.ncbi.nlm.nih.gov/pubmed/25726788
- Khaziakhmetova et al (2015) Experimental comparative study of the analgesic activity of the diurnal anxiolytic mebicar, amitriptyline, and diazepam https://www.ncbi.nlm.nih.gov/pubmed/26036004
- V Vorob’eva, V Repina (2016) An open comparative observational study of the efficacy and safety of adaptol in anxiety-asthenic disorders in patients with chronic cerebral ischemia https://www.ncbi.nlm.nih.gov/pubmed/27070467
- J Zhitkova, D Hasanova (2017) An experience of using mebicar in patients with autonomic dysfunction associated with anxiety disorder https://www.ncbi.nlm.nih.gov/pubmed/29265088
- Kim et al (2018) Preventive Effect of Mebicar and Ginsenoside Rg1 on Neurobehavioral and Immunological Disruptions Caused by Intermittent Unpredictable Stress in Mice https://www.ncbi.nlm.nih.gov/pubmed/29920498
- Kuzmenko et al (2020) [Current trends in the treatment of chronic recurrent bacterial cystitis] https://pubmed.ncbi.nlm.nih.gov/33377679/
- Kotova et al (2022) [Sleep disorders in post-COVID syndrome – a problem of psychiatry or neurology?] https://pubmed.ncbi.nlm.nih.gov/35759562/
4.2
Based on 18 Reviews
(13)
(1)
(1)
(1)
(2)
12/29/2023
Drew Y.
Verified Buyer
US
Not much of an effect
Gave this a try and it had no perceptible effect. I'd try it on days where I was in a sort of 'wire but tired' state which I figured this would be well-suited to help with, but even with experimenting up to 4 pills I got nothing from it. Maybe it would have worked under different circumstances but it was a no-go for me. I won't say I'm never going to try it again, but given how few pills you get in relation to its price the odds are low.
01/10/2024
Hi Drew, we're sorry to hear that the product didn't work for you. 😔 For most nootropics, the effect can be varied for different people. It strongly depends on personal conditions, so we always recommend consulting a specialist before taking any medication.
06/06/2023
Lauren B.
Verified Buyer
US
Legit
The product was legit and as expected:)
06/07/2023
Hi Lauren, thank you for your feedback.! :)
05/08/2023
William M.
Verified Buyer
US
Adaptol
Best product I know of to calm the nerves. Non addictive and safe. No side effects. Thank you CosmicNootropic.
05/10/2023
Hi William, thank you for your feedback! We are happy to hear that you are satisfied with the product. :)
02/18/2023
Inna S.
Verified Buyer
US
Very happy with variety of choices and costumer service!
Great variety of choices, fast delivery. Overall, very happy
02/19/2023
Dear Inna, thank you very much for your kind feedback!
01/18/2023
Inna S.
Verified Buyer
US
Very happy with variety of choices and costumer service!
Excellent costumer service, on-time delivery, great variety of supplements, reasonable prices.
01/22/2023
Thank you Inna, we really appreciate your feedback!
10/24/2022
David N.
Verified Buyer
FR
I never received this item
I'n not giving a bad review, i imagine it's not easy witg all the delivery process but i want to let yoyu know that I never received it
10/26/2022
Hi David, I'm sorry that your item did not arrive. We have contacted you via email to solve this problem. Please check your inbox!
01/25/2022
Jeffrey D.
Verified Buyer
US
Arrived on time and all, but I'm not sure if the pills did much.
I bought these to help with anxiety and sleep as I quit tobacco. It's kinda hard to subjectively say, but I didn't notice much of an effect. I tried taking 500mg and 1,000mg doses and didn't notice anything. I didn't experience anything negative or positive.
03/09/2022
Dear Jeffrey, Sorry for the unpleasant experience. The thing is that the effect varies from person to person depending on the personal conditions. That's why we always recommend to consult a specialist before taking any meds. If needed, please reach out to [email protected] and we can answer your questions in more detail.
02/12/2021
Anthony M.
Verified Buyer
US
Exactly as advertised!
Exactly as advertised! Very effective (2 tabs) to maintain focus and stay calm and in control in stressful situations! Which may be M-F at your job? This is great help!!
01/24/2021
Samuel L.
Verified Buyer
US
Effective product
Since I've started taking this product, its effects haven't suppressed the better side of my personality. It's still early in the treatment process, but my sense of this product is positive as it looks to be reflecting the effects indicated by trial research.
12/25/2019
Felipe S.
Verified BuyerGreat for rebalance
Great product. I used it to recover from an intensive practicum period. Sleep well and mood increased positively in about a week. However, it is a little on the strong side. We all react differently to chemistry changes in our neurons. I would buy this again.
10/18/2018
Michelle A.
Verified BuyerSide effects with Mebicar
Horrible side effects, allergic rhinitis burning on tongue, throat and mouth. Severe Headache. Would recommend nobody buy this product
01/01/1970
Hello Michelle, Without knowing your specific case we cannot recommend anything in this situation. There has been reports of such side effects previously, but they are rear and manifest themselves only if the patient is sensitive to the Mebicar. We strongly recommend to stop using Adaptol if you feel any worrying side effects. They should disappear as soon as you stop taking the supplement. Best regards, Andrey
10/16/2018
Nadezhda M.
Verified BuyerGreat service and product
I was very satisfied with the product and plan to do business again with them in the future.
10/16/2018
Nadezhda M.
Verified BuyerGreat service and product
I was very satisfied with the product and plan to do business again with them in the future.
02/20/2018
Ola A.
Verified BuyerSo many side effects
This product isn’t good at all, the side effects aren’t listed because not enough/ no clinical trail was conducted. After I took it, it make me feel drowsy I would sleep for 12hrs or longer. I started having different emotional feelings(very bad emotions and thought(s)), I felt like crying but couldn’t cry (this almost drove me crazy). I didn’t ********** (this is on of the side effect when taking drugs that effects the NS),immediately I stopped taking it after two days my ************ came. If all these side effects came and the medication made my anxiety good it would have been great and worth it, but didn’t do **** for my anxiety just gave me negative effects( my anxiety isn’t extreme it’s just occurs occasionally when I have presentations and something important coming up). I won’t ever buy these sh** every again, I got four packs and I had to throw them out, beware of self medication like these,( it even states it might not work, and it didn’t). Don’t waste your money, time and health on something you aren’t sure would work or help u, don’t take chances on your health.
01/01/1970
Hi Ola, We are sorry for your negative experience with Adaptol. As all the other medications it has negative side effects that may be severe, if the drug is taken excessively or patient has hypersensitivity to the ingredients of the drug. Such medication usually have cumulative effect, so positive perks don't come instantly. But, in any case, it was a wise decision to stop the treatment, since the side effects were so severe for you. All side effects should fade after you stop taking the drug, so there are no additional steps to be taken in that direction. If you need any other information or help don't hesitate to contact us any time via our e-mail. Regards, Andrey
01/13/2018
John C.
Verified BuyerDelivery to Malta
Excellent customer service and products
02/05/2017
Krys
Verified BuyerWORKS!
Quick delivery. Customer service excellent. Product itself as advertised and works. Product delivers subtle calmness and HD vision. Dosing is a bit inconvenient as you need more than one pack for it to last a month.
02/05/2017
Martin R.
Verified BuyerALL GOOD SO FAR.
Ordered 3 boxes of Adaptol. I felt I took a risk here as from previous experience I know there are plenty of scammers on the scene. I was delighted to receive my order precisely one week from day of order. The tracking was a reassurance too and also fit for purpose (a rarity now sadly). Package arrived undamaged and not tampered with by customs (maybe I was lucky). The product looks legit but yet to test. Anyway, I'm pleasantly surprised and will without doubt use this vendor again soon. Thanks Ololoman.
02/05/2017
Brian M.
Verified BuyerNOVEL COMPOUND, INTERESTING RESULTS.
The results I got from Mebicar are... a little hard to explain. I'm on week 3 of 500mg 2xday, and I feel good. Actually, really good. I suffer from sometimes crippling social anxiety, and have recently been tasked with broadcasting a webinar to over 600 of my organizations locations. Anxiety setting in well before broadcast, I decided to give Mebicar a try. I'm glad I did. I don't feel anything else but... calm. No sides, no sedation. No tolerance build as far as I can tell. Just a sense of calm, like everything is going to be okay and you're empowered to make it so. I've become much more social, talkative, and confident. Mebicar is definitely a compound I can see myself coming back to again and again. Try it out for yourself.
Nadezhda M. Verified Buyer
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